The foundational fertility supplement for women trying to conceive naturally, with PCOS, or preparing for IVF. The baby you're hoping for starts with one egg. Ovelle restores the cellular energy your eggs are losing, calms the inflammation draining it, and protects them in their full 90-day window.
Ovelle Fertility
- Restores NAD+, the cellular energy your eggs lose as you age
- Calms the inflammation draining your eggs
- Protects egg quality through the full 90-day development window
Choose your protocol:
Recommended 3-month protocol matches your egg development cycle.
60-Day Money Back Guarantee
Lauren T
"My RE told me at 38 that my eggs were 'too old.' I wasn't ready to accept that. 12 weeks on Ovelle and for the first time in this whole process, I feel like I'm actually supporting my body instead of fighting it."
What women are saying
From women who gave their eggs the full 90 days
I Finally Felt Something
I'd been taking CoQ10 and a prenatal for two years and honestly I couldn't tell you if either one did a single thing. That's the part nobody warns you about, you just swallow and hope. Ovelle Fertility is the first one I could actually feel. Around week five the 4pm crash I'd been planning my whole day around just stopped happening, and my cycle has arrived on time three months running. It's the first bottle on my shelf I'm not taking on faith.
My RE Actually Read the Label
I brought the bottle to my RE fully expecting him to brush it off. Instead he read the label twice and said it was the first NAD+ formula he'd seen dosed for the egg cycle instead of anti-aging, and that he had no issue with me taking it alongside my prenatal. That was the moment I stopped feeling like I was gambling on another internet supplement. Twelve weeks in and I'm still on it.
It Isn't Another CoQ10
I'd already done CoQ10, then ubiquinol, then inositol, then DHEA. Every one of them expensive, every one of them nothing. What finally made sense to me is that all of them need NAD+ to work and mine was long gone. This isn't another antioxidant to add on top. It's the fuel underneath the ones I was already buying. I kept my whole shelf. It just finally has something under it.
I Almost Threw All Of It Out
I had a bin bag open on the counter and I was about two minutes from throwing away three years of bottles. I gave it one more 90 days instead, which felt insane at the time, and I'm glad I did. I'm sleeping through the night. I'm not asleep on the couch by 6pm. I got through my sister's baby shower without needing to lie down afterwards. Nothing else I tried ever gave me that.
Two Capsules Instead of Nine
I was taking nine capsules a day across five different bottles and spending over $200 a month for the privilege. Ovelle Fertility is two capsules with breakfast, and it's the only one I'd fight to keep. It costs less per day than my prenatal, and it's the one doing the job the rest of them were waiting on. I don't feel like I'm drowning in bottles anymore.
The Afternoons Came Back First
Nothing happened for the first three weeks and I nearly quit, so I want to say that part out loud. Then the afternoons came back. I stopped hitting the wall at 3 or 4 the way I had for years, and my husband noticed before I did. I'm on my third bottle now, because they told me straight that the eggs take the full 90 days and I wanted to give it the entire window.
The most overlooked driver of declining egg quality after 35 isn't your age. It's a single enzyme called CD38.
CD38 does one job. It consumes NAD+, the fuel every egg you have depends on to develop, and it gets better at it every year. This is the chain it sets off.
01
The Cause
CD38 Overactivity
An enzyme called CD38 more than doubles in aging ovaries, and consuming NAD+ is the only thing it does. Chronic inflammation switches on more of it, so the drain accelerates as you age. Nothing you've been told to try touches CD38
02
What It Takes
NAD+ Depletion
NAD+ is the cellular fuel your eggs run on. By your mid-30s, up to 50% of it is gone. By 40, more than 60%. Your egg still has to run the most energy-hungry job in your body, on half the power it had at 25.
03
The Damage
Oxidative Stress
An egg with no energy left cannot defend itself. Across the 90 days it spends maturing, it develops in a high-stress environment, and the damage is done before it is ever released.
This is why nothing has moved the needle. Whatever you've tried, the tracking, the diet changes, the supplements, the waiting, all of it lands downstream of one enzyme quietly draining the energy everything else depends on. The effort was real. The foundation just wasn't there yet.
THE ENERGY YOUR EGGS NEED
Your most energy-hungry cell is the one trying to make a baby.
MITOCHONDRIA PER CELL
Brain cell
2,000
Muscle cell
2,000
Liver cell
2,000
Heart cell
5,000
Your egg cell
200,000+
Your egg cell needs 40x more energy than the cells keeping you alive. After 35, the system that supplies it has dropped by half. Ovelle Fertility is what we built to restore it.
How it works
Three things your eggs need before anything else works.
Ovelle Fertility is the foundational fertility supplement built around all three goals. The first step for women TTC naturally, managing PCOS, or prepping for IVF retrieval.
01
Restore
Replenish the NAD+ your eggs lose with age. Give them the cellular energy to develop the way they're supposed to.
02
Calm
Reduce the chronic inflammation that activates CD38 and drains your NAD+. Fix the leak so the restoration actually holds.
03
Protect
Shield developing eggs from oxidative stress across the full 90-day maturation window. Give every egg you ovulate the chance to mature in a healthier environment.
The next 90 days will produce the eggs you ovulate three months from now
Whatever cellular environment they develop in is what you're working with. The window doesn't reopen. It just keeps moving forward, with or without the foundation.
The next chapter starts with what you do today.
Our Formula
What's inside Ovelle Fertility
Three research-backed ingredients at clinical doses. Because every egg counts.
Restore
Nicotinamide Riboside Hydrogen Malate
500
mg per serving
Restores NAD+, the cellular fuel eggs run on to mature, divide, and develop. By 35, half of it is gone. This is where egg quality starts.
Calm
R-Alpha Lipoic Acid
400
mg per serving
Calms the inflammation and oxidative stress that build up where your eggs develop. Recharges your body's own antioxidant defenses so they keep protecting your cells instead of burning out.
Protect
Trans-Pterostilbene
100
mg per serving
Turns on your cells' own defense system, so your body creates its protection instead of just absorbing it. That defense stays active where your eggs develop. Full coverage across the 90 days they need to mature.
How Ovelle Fertility compares
Whether you're trying naturally, managing PCOS, or preparing for IVF, here's how Ovelle Fertility fits into your protocol.
| Ovelle Fertility | OTHER NAD+ SUPPLEMENTS | COQ10 | Prenatal | |
|---|---|---|---|---|
| Built for fertility, not anti-aging | ||||
| Restores cellular NAD+ | ||||
| Calms inflammation draining NAD+ | ||||
| Includes 90-day cellular support ingredients | ||||
| Supports PCOS metabolic function | ||||
| Three-pillar formula (Restore, Calm, Protect) | ||||
| Works alongside your prenatal and anything else you take |
The first step to a healthy egg environment costs less than your prenatal
What women try when nothing works:
One IVF cycle
$15K-$30K
Before any cellular prep
Average monthly fertility stack
$200-$300
CoQ10, prenatals, inositol, others
Ovelle Fertility on the 3-month protocol
$1.45/day
The foundational step every protocol depends on
At $1.45 a day, Ovelle Fertility is less than 1% of a single IVF cycle. It's the first step, the one everything else in your journey builds on.
Our standards
Built differently. Tested independently.
Every batch is third-party tested. Every ingredient is fully disclosed. Every dose is based on published research. Nothing hidden. Nothing exaggerated.
01
Third-party tested
Every batch is verified by an independent lab. Certificate of Analysis available on request.
02
Full transparency
Every ingredient and dose on the label. No proprietary blends. No fillers.
03
Research-backed doses
Clinical doses based on published studies. No token amounts to pad the label.
04
60-day guarantee
Full refund, no questions asked. Keep the bottle if it doesn't work for you.
Frequently Asked Questions
What's in Ovelle Fertility, and how do I take it?
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Each bottle is a 30-day supply. Take 2 capsules together once a day with water, either with or without food.
Each daily serving contains Nicotinamide Riboside Hydrogen Malate 500mg, R-Alpha Lipoic Acid 400mg, and Trans-Pterostilbene 100mg. No fillers or synthetic additives.
A few notes. Best taken alongside a prenatal with biotin and thiamine (B1). If you take thyroid medication, separate dosing by at least 4 hours. Discontinue once you receive a positive pregnancy test.
For best results, take Ovelle daily for at least 90 days, the length of one full egg development cycle.
How is Ovelle Fertility different from CoQ10 or other fertility supplements?
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CoQ10 is downstream. Ovelle Fertility is upstream.
Most fertility supplements work at one point in the cellular energy chain. CoQ10 carries electrons. Prenatals provide raw materials. Inositol supports hormone signaling. All of them depend on NAD+, the molecule that powers the entire chain.
NAD+ drops up to 50% through your 30s. Without enough of it, your mitochondria can't fully use the CoQ10 you're already taking. Ovelle Fertility restores that foundation. It's not a replacement for your stack. It's what makes the rest of it work harder.
Can I take Ovelle Fertility with my current stack?
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Yes. Ovelle is safe to take alongside a prenatal multivitamin, CoQ10, myo-inositol, vitamin D, omega-3s, and most other fertility supplements. In fact, the R-ALA in Ovelle helps recycle your CoQ10 and other antioxidants so they work harder.
A few notes. Take Ovelle alongside a prenatal that contains biotin and thiamine (B1). If you take thyroid medication, separate dosing by at least 4 hours. If you take blood thinners, check with your doctor before starting.
If you're not sure how Ovelle fits with something you're taking, email hello@rezaorigin.com
Will Ovelle Fertility help if I have low AMH?
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AMH measures how many eggs you have left. Ovelle Fertility supports the quality of the eggs you have, not the quantity.
No supplement raises AMH or creates new follicles. What Ovelle does is support the cellular environment those eggs develop in. When you have fewer eggs, every single one matters more, and giving each one the best mitochondrial foundation is what Ovelle was built for.
If your doctor has told you that donor eggs are your only option, please talk to them before changing your protocol. Ovelle is not a treatment for low ovarian reserve. It's the cellular foundation that supports the eggs you have.
Will Ovelle Fertility work if I have PCOS?
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Yes. Ovelle was designed with PCOS in mind from the start.
PCOS is increasingly understood as a cellular energy problem, not just a hormonal one. The R-Alpha Lipoic Acid in Ovelle has strong human research behind it for PCOS, with multiple clinical studies showing support for insulin sensitivity, menstrual cycle patterns, and the cellular environment eggs develop in.
If you're already taking myo-inositol, Ovelle pairs well with it. The two work on different parts of the same problem.
I've had a miscarriage. Is Ovelle Fertility right for me?
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We're so sorry. Take whatever time you need.
Nothing you took or didn't take caused your loss. And when you're ready to try again, the eggs you'll ovulate are new ones. They start developing months before ovulation, and Ovelle supports the environment they mature in from the beginning.
If your doctor has recommended waiting, follow their timeline. Ovelle can be part of how you prepare while you do.
I just stopped birth control. Should I start this now?
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Yes, and it's one of the best times to start.
Birth control didn't damage your fertility. It paused the signals you'd normally use to read your cycle, which is why so many women come off the pill and feel like they don't know where their body stands. While your cycle finds its rhythm, your eggs are already moving through their 90-day development window.
Start Ovelle now and the eggs you ovulate a few months from now mature with the energy they need from the start of that window. It also pairs well with a prenatal, which most doctors recommend starting before conception anyway.
My doctor told me to lose weight before trying. Will this still help?
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Yes. Your doctor is right that weight matters, and it isn't the only thing that does.
Egg quality also depends on the cellular energy available during the roughly 90 days each egg spends developing, and that clock keeps running while you work on the scale. The eggs you'll ovulate a few months into your plan are forming right now.
So do both. Keep the plan your doctor gave you, take Ovelle alongside it, and every egg in the meantime develops with more of what it needs.
I'm preparing for IVF or just had a failed cycle. When should I start?
+
The ideal window is 60 to 90 days before egg retrieval.
Eggs take about 90 days to fully mature. The cellular environment they develop in during that window determines their quality at retrieval. Starting Ovelle 60 to 90 days before your retrieval gives the formula time to support an entire egg maturation cycle.
If you've just had a failed cycle, your next cohort of eggs is already developing right now. The work happens in the cells that will become the eggs you retrieve months from now.
Always talk to your reproductive endocrinologist before starting any new supplement during IVF prep.
Is Ovelle Fertility safe to take while actively trying to conceive? What do I do if I get pregnant?
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Yes. Ovelle is formulated specifically for the pre-conception window. You can take it while actively trying to conceive, including during cycles where you may end up pregnant.
If you receive a positive pregnancy test, discontinue Ovelle and switch fully to your prenatal vitamin. The formula is designed for the cellular preparation phase before pregnancy, not for ongoing use during pregnancy.
If you have remaining bottles, hold onto them. Many women use Ovelle between pregnancies or for future cycles. You can also gift unopened bottles to a friend who's trying.
Why is the 3-month protocol the recommended option?
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Because it matches one full egg development cycle.
Eggs take approximately 90 days to mature from a primordial follicle to an ovulation-ready egg. The cellular environment they develop in during those 90 days shapes their quality at ovulation. A 1-month supply only covers the final third of that window.
The 3-month protocol gives the formula time to support a complete maturation cycle from start to finish. The 6-month option covers two full cycles, which is useful for IVF prep or for women who want the longest possible runway.
How long until I notice something, and what if it doesn't work?
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Most women notice changes in energy and cycle patterns within the first 4 to 6 weeks. Egg quality changes happen at the cellular level over 90 days, so the most meaningful results come at the end of a full protocol cycle.
Fertility is complex and individual. We can't promise specific outcomes, and any supplement that does is being dishonest with you. What we can promise is the cellular foundation egg development depends on, plus a 60-day money-back guarantee.
If you've completed 60 days of Ovelle and feel it isn't right for you, email hello@rezaorigin.com and we'll process your refund.
60-Day Money-Back Guarantee
You're already on your way.
You've researched. You've read. You've taken the test most women never take, admitting that something has to change in the foundation, not on top of it. The 3-month protocol matches one full egg development cycle. Start the one your eggs are already entering.
