The foundational fertility supplement for women trying to conceive naturally, with PCOS, or prepping for IVF. Built around the three things your eggs need before any other supplement can work.
Ovelle Fertility
- Restores NAD+, the cellular energy your eggs lose after 35
- Calms the inflammation draining your eggs
- Protects egg quality through the full 90-day development window
Choose your protocol:
Recommended 3-month protocol matches your egg development cycle.
"My RE told me at 38 that my eggs were 'too old.' I wasn't ready to accept that. 12 weeks on Ovelle and for the first time in this whole process, I feel like I'm actually supporting my body instead of fighting it."
The most overlooked driver of decreasing egg quality in women 30+ today is Cellular Energy Decline (CED)
CED happens when the three systems that power egg development start breaking down:

NAD+ Depletion
By 30+, your cellular NAD+ has dropped by up to 50%. By 40, over 60%. Your eggs lose the energy they need to develop properly and respond to your body's fertility signals.

CD38 Overactivity
An enzyme called CD38 more than doubles in aging ovaries. It drains whatever NAD+ you have left. The more chronic inflammation in your body, the more CD38 activates, and the faster your cellular energy disappears.

Oxidative Stress
During the 90-day maturation window, eggs are vulnerable to oxidative damage. Without protective pathways active, the eggs you ovulate develop in a high-stress environment, affecting quality before they're even released.
When all three systems break down together, no amount of CoQ10 or prenatals can compensate. Your stack is working on top of a foundation that isn't there anymore.
Your most energy-hungry cell is the one trying to make a baby.
Your egg cell needs 40x more energy than the cells keeping you alive. After 35, the system that supplies it has dropped by half. Ovelle Fertility is what we built to restore it.
Three things your eggs need before anything else works.
Ovelle Fertility is the foundational fertility supplement built around all three goals. The cellular groundwork for women TTC naturally, managing PCOS, or prepping for IVF retrieval.
Restore
Replenish the NAD+ your eggs lose with age. Give them the cellular energy to develop the way they're supposed to.
Calm
Reduce the chronic inflammation that activates CD38 and drains your NAD+. Fix the leak so the restoration actually holds.
Protect
Shield developing eggs from oxidative stress across the full 90-day maturation window. Give every egg you ovulate the chance to mature in a healthier environment.
The next 90 days will produce the eggs you ovulate three months from now
Whatever cellular environment they develop in is what you're working with. The window doesn't reopen. It just keeps moving forward, with or without the foundation.
The next chapter starts with what you do today.
What's inside Ovelle Fertility
Three research-backed ingredients at clinical doses. Because every egg counts.

Nicotinamide Riboside Hydrogen Malate
Restores NAD+, the cellular fuel your eggs depend on to mature, divide, and develop properly. NAD+ drops by half after 35. This is the foundation that makes everything else in your fertility stack work.

R-Alpha Lipoic Acid
Calms the inflammation and oxidative stress that build up where your eggs develop. Recharges your CoQ10, vitamin C, and vitamin E so they keep protecting your cells instead of burning out.

Trans-Pterostilbene
Turns on your cells' natural defense system so your eggs stay protected while they develop. Absorbed 4x better than resveratrol, so more reaches your cells at a lower dose. Works across the full 90 days your eggs need to mature.
How Ovelle Fertility compares to what's already on your shelf
Whether you're trying naturally, managing PCOS, or preparing for IVF, here's how Ovelle Fertility fits into your protocol.
| Ovelle Fertility | OTHER NAD+ SUPPLEMENTS | COQ10 | Prenatal | |
|---|---|---|---|---|
| Built for fertility, not anti-aging | ||||
| Restores cellular NAD+ | ||||
| Calms inflammation draining NAD+ | ||||
| Includes 90-day cellular support ingredients | ||||
| Supports PCOS metabolic function | ||||
| Three-pillar formula (Restore, Calm, Protect) | ||||
| Works with your existing stack |
The cellular foundation costs less than your prenatal.
What women try when nothing works:
At $1.45 a day, Ovelle Fertility is less than 1% of a single IVF cycle, and it's the step that gives every other dollar in your protocol a better chance of working.
Built differently. Tested independently.
Every batch is third-party tested. Every ingredient is fully disclosed. Every dose is based on published research. Nothing hidden. Nothing exaggerated.
Third-party tested
SGS lab verified. Certificate of Analysis available on request, every batch.
Full transparency
Every ingredient and dose on the label. No proprietary blends. No fillers.
Research-backed doses
Clinical doses based on published studies. No token amounts to pad the label.
60-day guarantee
Full refund, no questions asked. Keep the bottle if it doesn't work for you.
Frequently Asked Questions
Each bottle is a 30-day supply. Take 2 capsules together once a day with water, either with or without food.
Each daily serving contains Nicotinamide Riboside Hydrogen Malate 500mg, R-Alpha Lipoic Acid 400mg, and Trans-Pterostilbene 100mg. No fillers or synthetic additives.
A few notes. Best taken alongside a prenatal with biotin and thiamine (B1). If you take thyroid medication, separate dosing by at least 4 hours. Discontinue once you receive a positive pregnancy test.
For best results, take Ovelle daily for at least 90 days, the length of one full egg development cycle.
CoQ10 is downstream. Ovelle Fertility is upstream.
Most fertility supplements work at one point in the cellular energy chain. CoQ10 carries electrons. Prenatals provide raw materials. Inositol supports hormone signaling. All of them depend on NAD+, the molecule that powers the entire chain.
NAD+ drops up to 50% through your 30s. Without enough of it, your mitochondria can't fully use the CoQ10 you're already taking. Ovelle Fertility restores that foundation. It's not a replacement for your stack. It's what makes the rest of it work harder.
Yes. Ovelle is safe to take alongside a prenatal multivitamin, CoQ10, myo-inositol, vitamin D, omega-3s, and most other fertility supplements. In fact, the R-ALA in Ovelle helps recycle your CoQ10 and other antioxidants so they work harder.
A few notes. Take Ovelle alongside a prenatal that contains biotin and thiamine (B1). If you take thyroid medication, separate dosing by at least 4 hours. If you take blood thinners, check with your doctor before starting.
If you're not sure how Ovelle fits with something you're taking, email hello@rezaorigin.com
AMH measures how many eggs you have left. Ovelle Fertility supports the quality of the eggs you have, not the quantity.
No supplement raises AMH or creates new follicles. What Ovelle does is support the cellular environment those eggs develop in. When you have fewer eggs, every single one matters more, and giving each one the best mitochondrial foundation is what Ovelle was built for.
If your doctor has told you that donor eggs are your only option, please talk to them before changing your protocol. Ovelle is not a treatment for low ovarian reserve. It's the cellular foundation that supports the eggs you have.
Yes. Ovelle was designed with PCOS in mind from the start.
PCOS is increasingly understood as a cellular energy problem, not just a hormonal one. The R-Alpha Lipoic Acid in Ovelle has strong human research behind it for PCOS, with multiple clinical studies showing support for insulin sensitivity, menstrual cycle patterns, and the cellular environment eggs develop in.
If you're already taking myo-inositol, Ovelle pairs well with it. The two work on different parts of the same problem.
The ideal window is 60 to 90 days before egg retrieval.
Eggs take about 90 days to fully mature. The cellular environment they develop in during that window determines their quality at retrieval. Starting Ovelle 60 to 90 days before your retrieval gives the formula time to support an entire egg maturation cycle.
If you've just had a failed cycle, your next cohort of eggs is already developing right now. The work happens in the cells that will become the eggs you retrieve months from now.
Always talk to your reproductive endocrinologist before starting any new supplement during IVF prep.
Yes. Ovelle is formulated specifically for the pre-conception window. You can take it while actively trying to conceive, including during cycles where you may end up pregnant.
If you receive a positive pregnancy test, discontinue Ovelle and switch fully to your prenatal vitamin. The formula is designed for the cellular preparation phase before pregnancy, not for ongoing use during pregnancy.
If you have remaining bottles, hold onto them. Many women use Ovelle between pregnancies or for future cycles. You can also gift unopened bottles to a friend who's trying.
Because it matches one full egg development cycle.
Eggs take approximately 90 days to mature from a primordial follicle to an ovulation-ready egg. The cellular environment they develop in during those 90 days shapes their quality at ovulation. A 1-month supply only covers the final third of that window.
The 3-month protocol gives the formula time to support a complete maturation cycle from start to finish. The 6-month option covers two full cycles, which is useful for IVF prep or for women who want the longest possible runway.
Most women notice changes in energy and cycle patterns within the first 4 to 6 weeks. Egg quality changes happen at the cellular level over 90 days, so the most meaningful results come at the end of a full protocol cycle.
Fertility is complex and individual. We can't promise specific outcomes, and any supplement that does is being dishonest with you. What we can promise is the cellular foundation egg development depends on, plus a 60-day money-back guarantee.
If you've completed 60 days of Ovelle and feel it isn't right for you, email hello@rezaorigin.com and we'll process your refund.
You're already on your way.
You've researched. You've read. You've taken the test most women never take, admitting that something has to change in the foundation, not on top of it. The 3-month protocol matches one full egg development cycle. Start the one your eggs are already entering.